1-Ethyl-2-pyrrolidone

Superior Solvent Efficiency: Combines strong solvency with a low dielectric constant and minimal volatility, making it an effective reaction medium for complex chemical processes.

Effective Penetration Enhancer: Interacts directly with the multilamellar liposome structure of stratum corneum lipids to significantly boost transdermal absorption.

Versatile Industrial Intermediate: Serves as a key building block in polycarboxylic acid synthesis while accommodating specialized processes involving viscosity adjustments and hydrogen bonding.

Low Vapor Pressure: Minimizes evaporative loss during use, ensuring controlled operational environments and reduced emissions.

Product Description
1-Ethyl-2-pyrrolidone
Product Application

Products Description of Potassium phosphate CAS#778-53-2

1-Ethyl-2-pyrrolidone (NEP) is a clear, colorless liquid engineered to function as an advanced aprotic solvent. Distinguished by its strong solvency, low volatility, and low dielectric constant, it performs reliably across diverse chemical processes. Beyond its primary solvency capabilities, it plays a strategic role in facilitating transdermal drug delivery and acting as a chemical intermediate in organic synthesis.

1-Ethyl-2-pyrrolidone

1-Ethyl-2-pyrrolidone Chemical Properties

Melting point 87.5-88.5 °C
Boiling point 97 °C/20 mmHg (lit.)
Density 0.992 g/mL at 25 °C (lit.)
Vapor pressure 18Pa at 20℃
Refractive index n20/D 1.465(lit.)
Fp 169 °F
Storage temp. Sealed in dry,Room Temperature
Pka-0.41±0.20(Predicted)
Form Liquid
Color Clear
PH8-9 (100g/l, H2O, 20℃)
Explosive limit1.3-7.7%(V)
Water Solubility 1000g/L at 23℃
BRN 107971
InChIKeyZFPGARUNNKGOBB-UHFFFAOYSA-N
LogP-0.2 at 20℃
CAS DataBase Reference2687-91-4(CAS DataBase Reference)
NIST Chemistry Reference1-Ethyl-2-pyrrolidinone(2687-91-4)
EPA Substance Registry System2-Pyrrolidinone, 1-ethyl- (2687-91-4)

Safety Information

Hazard Codes Xn,T
Risk Statements 22-36-62-41-61
Safety Statements 26-36-45-36/37/39-53
WGK Germany 1
RTECS UY5769250
TSCA Yes
HS Code 29337900
1-Ethyl-2-pyrrolidone

Product Application

Safety and Toxicological Profile

Strict safety and handling protocols must be enforced due to the hazardous characteristics of this compound:

Reproductive Toxicity: Classified as a reproductive toxicant capable of impairing reproductive functions or causing developmental issues in males and females.

Neurological Risk: Acts as a potential neurotoxin associated with Acute Solvent Syndrome upon exposure.

Hepatotoxicity: Identified as an occupational hepatotoxin, presenting risks of toxic effects to the liver through workplace inhalation, absorption, or ingestion.

1-Ethyl-2-pyrrolidone