Products Description of Guanidine Hydrochloride 99.5% CAS#50-01-1
Guanidine Hydrochloride, also referred to as Carbamidine Hydrochloride, is a white to pale yellow crystalline compound with very low solubility in acetone, benzene, and ether. Owing to its versatile chemical properties, it is widely utilized as a valuable intermediate in the synthesis of pharmaceuticals, agrochemicals, dyes, and various other organic compounds.
As an important pharmaceutical raw material, Guanidine Hydrochloride is used in the manufacture of several medicinal products, including sulfadiazine, sulfamethylpyrimidine, sulfadimethylpyrimidine, and folic acid. In addition, it can be used as an antistatic additive in synthetic fibers, helping to reduce static buildup and improve the functional performance of fiber materials.
Product Parameters of Guanidinehydrochloride99.5%CAS#50-01-1
| CAS | No. 50-01-1 |
| CID | 5742 |
| EINECS(EC#) | 200-002-3 |
| Molecular Formula | CH6ClN3 (isomer) |
| Inchi | InChI=1S/CH5N3.ClH/c2-1(3)4;/h(H5,2,3,4);1H |
| InChIkey | PJJJBBJSCAKJQF-UHFFFAOYSA-N |
| Canonical Smiles | C(=N)(N)N.Cl |
| Isomers Smiles | C(=N)(N)N.Cl |
| Density | 1.18 g/mL at 25 °C(lit.) |
| Melting point | 180-185 °C(lit.) |
| Boiling point | 132.9 °C at 760 mmHg |
| Refractive index | n20/D 1.465 |
| Flash Point | 34.2 °C |
| Precise Quality | 95.025 |
| PSA | 75.89 |
| logP | 1.1409 |
| Solubility | H2O: 6?M, clear, colorless |
| Appearance | DryPowder; DryPowder, Liquid |
| Storage | Store at RT. |
| Chemical Properties | White cryst. powder |
| Color/Form | White to slightly yellow |
| Odo | Odorless |
| PH | 4.5-5.5 (100g/l, H2O, 20℃) |
| Water Solubility | H2O: 2280 g/L (20 oC) |
| Stability | Stable. Hygroscopic. Incompatible with strong oxidizing agents. |
| StorageTemp | Store at RT. |
Product Application of Guanidine Hydrochloride 99.5% CAS#50-01-1
Guanidine Hydrochloride is widely employed as a versatile intermediate in the synthesis of pharmaceuticals, agrochemicals, dyes, and other specialty chemicals.
It is commonly used as a starting material for the preparation of pyrimidine derivatives, including 2-aminopyrimidine, 2-amino-6-methylpyrimidine, and 2-amino-4,6-dimethylpyrimidine. It also plays an important role in the manufacture of sulfonamide pharmaceuticals, such as sulfadiazine, sulfamethylpyrimidine, and sulfamethazine.
Guanidine Hydrochloride, as well as guanidine nitrate, can undergo a reaction with ethyl cyanoacetate to form 2,4-diamino-6-hydroxypyrimidine, an intermediate used in the synthesis of folic acid for pharmaceutical applications. In addition, Guanidine Hydrochloride can be used as an antistatic agent in the production of synthetic fibers, helping to minimize static buildup and enhance material performance.
