Pagoclone

GABA Receptor Modulation: Pagoclone is a cyclopyrrolone compound that interacts with GABA (gamma-aminobutyric acid) receptors and modulates GABAergic neurotransmission.

Potential Effect on Stuttering: By influencing GABA(A) receptor activity, pagoclone has been investigated for its potential to reduce the frequency or severity of stuttering.

Distinct Cyclopyrrolone Structure: As a structurally distinctive cyclopyrrolone derivative, pagoclone exhibits pharmacological characteristics that differentiate it from conventional GABAergic compounds.

GABA(A) Partial Agonist Activity: Pagoclone acts as a partial agonist at GABA(A) receptors, producing selective modulation of inhibitory neurotransmission.

Product Description
Chemical Properties
Product Application

Product Description of Pagoclone CAS#133737-32-3

Pagoclone is a selective GABA (gamma-aminobutyric acid) receptor modulator that has been investigated for its potential to alleviate stuttering. As a cyclopyrrolone derivative, it acts as a partial agonist at GABA(A) receptors and modulates inhibitory neurotransmission, giving it a distinctive pharmacological profile.

Pagoclone

Pagoclone Chemical Properties

Boiling point 582.1±50.0 °C(Predicted)
density 1.273±0.06 g/cm3(Predicted)
pka1.62±0.30(Predicted)
InChIInChI=1S/C23H22ClN3O2/c1-14(2)7-10-16(28)13-19-17-5-3-4-6-18(17)23(29)27(19)21-12-9-15-8-11-20(24)25-22(15)26-21/h3-6,8-9,11-12,14,19H,7,10,13H2,1-2H3
InChIKeyHIUPRQPBWVEQJJ-UHFFFAOYSA-N
SMILESC1(=O)C2=C(C=CC=C2)C(CC(=O)CCC(C)C)N1C1=CC=C2C(=N1)N=C(Cl)C=C2

Pagoclone

Product Application of Pagoclone CAS#133737-32-3

Pagoclone is a selective modulator of GABA (gamma-aminobutyric acid) receptors that has been studied for its potential to help reduce stuttering. Structurally classified as a cyclopyrrolone derivative, it acts as a partial agonist at GABA(A) receptors, contributing to its distinctive pharmacological characteristics.

Pagoclone