Product Description of 2-Deoxy-D-Glucose CAS# 154-17-6
2-Deoxy-D-glucose is a glucose analog and antimetabolite structurally related to D-glucose. It can interfere with glucose metabolism and affect the formation of certain virus-specific glycoproteins. These properties have made it an important research compound for studying the replication of herpes simplex virus, various enveloped RNA and DNA viruses, as well as the growth and metabolism of cancer cells.
Because of its ability to influence cellular energy metabolism and glycolysis, 2-Deoxy-D-glucose has been extensively investigated for potential antiviral and anticancer applications. It has also attracted interest in healthcare-related products, cosmetic research, and formulations associated with anti-aging studies.
2-Deoxy-D-glucose is widely used as a biochemical and life-science research reagent, particularly in studies involving glycolysis inhibition, cellular metabolism, viral replication, and tumor biology. Its distinctive metabolic properties continue to support research and development across pharmaceutical, healthcare, cosmetic, and life-science fields.
2-Deoxy-D-glucose Chemical Properties
| Melting point | 146-147 °C(lit.) |
| Alpha | 45.5 º (c=2, H2O) |
| Boiling point | 211.61°C (rough estimate) |
| Density | 1.1738 (rough estimate) |
| Refractive index | 46.5 ° (C=1, H2O) |
| Storage temp | 2-8°C |
| Solubility | H2O: 50 mg/mL, clear, colorless to faintly yellow |
| Form | crystalline |
| Pka | pK1:12.52 (25°C) |
| Color | white |
| Water Solubility | Soluble in water. |
| Merck | 142904 |
| BRN | 1723331 |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month. Solutions in water are not stable and must be used within 1 working day. |
| InChIKey | PMMURAAUARKVCB-CEZCPVKQSA-N |
| LogP | -1.460 (est) |
| CAS DataBase Reference | 154-17-6(CAS DataBase Reference) |
| EPA Substance Registry System | D-arabino-Hexose, 2-deoxy- (154-17-6) |
| Hazard Codes | Xn,Xi |
| Risk Statements | 20/21/22-36/37/38 |
| Safety Statements | 24/25-37/39-36-26 |
| WGK Germany | 3 |
| RTECS | MQ3325000 |
| F | 46091 |
| TSCA | Yes |
| HS Code | 29400090 |
| Hazardous Substances Data | 154-17-6(Hazardous Substances Data) |
Product Application of 2-Deoxy-D-Glucose CAS# 154-17-6
2-Deoxy-D-glucose is a D-glucose derivative that acts as an antimetabolite and glycolysis inhibitor. By interfering with glucose metabolism and the synthesis of certain virus-specific glycoproteins, it has been widely studied for its effects on herpes simplex virus and other enveloped RNA and DNA viruses. Its influence on cellular energy metabolism has also made it an important compound in cancer research, including studies involving breast cancer cells.
