Benzyldimethylhexadecylammonium Chloride

Broad-Spectrum Antimicrobial Defense – Functions as a potent anti-infective and preservative agent, serving as a key therapeutic candidate for oral, pharyngeal, and ocular infection research.

Cationic Surfactant Properties – Acts as a high-performance quaternary ammonium surfactant, delivering valuable emulsifying and stabilizing functionality in drug formulation.

Lipophilic Membrane Interaction – Exhibits strong lipophilicity that enhances its binding affinity to biological membranes, amplifying both its anti-inflammatory and antimicrobial efficacy.

Multifunctional Pharmaceutical Excipient – Widely utilized in pharmaceutical manufacturing as an active excipient, preservative, and anti-inflammatory base.

Products Description
Chemical Properties
Product Application

Products Description of Benzyldimethylhexadecylammonium Chloride CAS#122-18-9

Benzyldimethylhexadecylammonium chloride (also known as Cetaxonium chloride or hexadecyldimethylbenzylammonium chloride) is a lipophilic cationic quaternary ammonium surfactant. It represents a defined single-chain component of commercial benzalkonium chloride mixtures (which typically combine n-C12​H25​, n-C14​H29​, and n-C16​H33​ alkyl homologues). 

Characterized by its hydrophobic nature and modest aqueous solubility, it serves as an efficient anti-infective agent, formulation surfactant, and pharmaceutical excipient. Due to its quaternary ammonium preservative and anti-inflammatory characteristics, it is heavily referenced in research focusing on mucosal, throat, and ophthalmic infection treatments.

Benzyldimethylhexadecylammonium Chloride

Benzyldimethylhexadecylammonium chloride Chemical Properties

Melting point 55-65 °C(lit.)
Boiling point 550.14°C (rough estimate)
Density 0.9089 (rough estimate)
Vapor pressure 0Pa at 25℃
Refractive index 1.6000 (estimate)
Storage temp. room temp
Solubility DMSO: 100 mg/mL (252.47 mM)
Form Powder
Color White to creamy-white
Water Solubility MODERATELY SOLUBLE
Merck 142,017
BRN 3802341
LogP3.022 at 25℃
CAS DataBase Reference122-18-9(CAS DataBase Reference)
EPA Substance Registry SystemBenzyl hexadecyl dimethyl ammonium chloride (122-18-9)
Benzyldimethylhexadecylammonium Chloride

Product Application of Benzyldimethylhexadecylammonium Chloride CAS#122-18-9

Beyond its central role in pharmaceutical synthesis and drug delivery, this compound fulfills diverse functional roles across chemical and industrial manufacturing:

Pharmaceutical Formulations: Serves as an active pharmaceutical raw material, preservative, anti-inflammatory agent, and solubilizing excipient.

Disinfection & Biocides: Functions as a primary bactericidal base and disinfectant for topical and surface anti-infective applications.

Chemical & Industrial Processing: Acts as an effective phase-transfer catalyst, emulsifier, and antistatic processing aid in specialized chemical formulations.

Benzyldimethylhexadecylammonium Chloride