Products Description of Phenol CAS#108-95-2
Phenol, also known as hydroxybenzene, has the molecular formula C₆H₅OH (C₆H₆O). It is typically found as a white crystalline solid and is valued for its distinctive chemical reactivity and broad industrial utility. Its reactive hydroxyl group, directly bonded to the aromatic benzene ring, enables phenol to participate in a wide range of chemical transformations.
Phenol serves as an important intermediate in the manufacture of various pharmaceuticals and fine chemicals, including compounds used in the production of aspirin. It is also extensively utilized in the production of resins, plastics, synthetic fibers, and nylon-related materials.
Historically, phenol has been used for its disinfecting properties, as it can affect proteins and cellular membranes. Beyond these applications, it is also employed in detergent manufacturing and analytical chemistry.
Due to its strong chemical activity and toxicological hazards, phenol requires appropriate handling, storage, and safety measures during use. Although it can undergo biodegradation under suitable environmental conditions, proper waste collection and treatment are important to reduce potential environmental impacts. With its combination of reactivity and versatility, phenol remains an important raw material in a wide range of industrial and chemical processes.
Phenol Chemical Properties
Melting point | 40-42 °C(lit.) |
Boiling point | 182 °C(lit.) |
density | 1.071 g/mL at 25 °C(lit.) |
vapor density | 3.24 (vs air) |
vapor pressure | 0.09 psi ( 55 °C) |
refractive index | n20/D 1.53 |
FEMA | 3223 | PHENOL |
Fp | 175 °F |
storage temp. | 2-8°C |
solubility | H2O: 50 mg/mL at 20 °C, clear, colorless |
form | |
pka | 9.89(at 20℃) |
Specific Gravity | 1.071 |
color | faintly yellow |
PH | 6.47(1 mM solution);5.99(10 mM solution);5.49(100 mM solution); |
Odor | Sweet, medicinal odor detectable at 0.06 ppm |
explosive limit | 1.3-9.5%(V) |
Odor Threshold | 0.0056ppm |
Odor Type | phenolic |
Water Solubility | 8 g/100 mL |
FreezingPoint | 41℃ |
Sensitive | Air & Light Sensitive |
Merck | 147241 |
JECFA Number | 690 |
BRN | 969616 |
Henry's Law Constant | 1.09 at 5 °C (average derived from six field experiments, Lüttke and Levsen, 1997) |
Dielectric constant | 4.3（10℃） |
Exposure limits | TLV-TWA skin 5 ppm (～19 mg/m3 ) (ACGIH, MSHA, and OSHA); 10-hour TWA 5.2 ppm (～20 mg/m3 ) (NIOSH); ceiling 60 mg (15 minutes) (NIOSH); IDLH 250 ppm (NIOSH). |
Stability: | Hygroscopic |
InChIKey | ISWSIDIOOBJBQZ-UHFFFAOYSA-N |
LogP | 1.47 at 30℃ |
CAS DataBase Reference | 108-95-2(CAS DataBase Reference) |
IARC | 3 (Vol. 47, 71) 1999 |
NIST Chemistry Reference | Phenol(108-95-2) |
EPA Substance Registry System | Phenol (108-95-2) |
Safety Information
Hazard Codes | T,C,F,Xn |
Risk Statements | 23/24/25-34-48/20/21/22-68-40-39/23/24/25-11-36-20/21/22-24/25 |
Safety Statements | 26-36/37/39-45-36/37-28A-28-24/25-1/2-36-16-7 |
RIDADR | UN 2821 6.1/PG 2 |
OEB | A |
OEL | TWA: 5 ppm (19 mg/m3), Ceiling: 15.6 ppm (60 mg/m3) [15-minute] [skin] |
WGK Germany | 2 |
RTECS | SJ3325000 |
F | 46257 |
Autoignition Temperature | 715 °C |
TSCA | Yes |
HazardClass | 6.1 |
PackingGroup | II |
HS Code | 29071100 |
Hazardous Substances Data | 108-95-2(Hazardous Substances Data) |
Toxicity | LD50 orally in rats: 530 mg/kg (Deichmann, Witherup) |
IDLA | 250 ppm |
